Main artery crossword clue
Hidden by default so you do not spoil it by accident. Hint: it starts with A and has 5 letters.
AORTA — the 5-letter solution to “Main artery”, entered at 21 Down in the Thomas Joseph crossword for November 24, 2021.
About this clue
“Main artery” appeared as 21 Down in the Thomas Joseph crossword on November 24, 2021, and the answer is 5 letters long. We have tracked this clue 7 times in Thomas Joseph puzzles, most recently on August 18, 2025.
Every time this clue has run
More clues from November 24, 2021
Full guide ›Frequently asked questions
What is the answer to “Main artery”?
In the Thomas Joseph crossword for Wednesday, November 24, 2021, the answer to “Main artery” is AORTA — 5 letters, entered at 21 Down.
Could the answer be different in my puzzle?
The same clue text can take different answers depending on the grid. Every time we have seen “Main artery” in the Thomas Joseph crossword the answer has been AORTA, but always check the letter count against your grid.
How many letters is the answer?
The answer has 5 letters and starts with A.
Is this the official Thomas Joseph site?
No. This is an independent solver’s reference. The Thomas Joseph crossword is published by King Features Syndicate.